The power of seed funding: CCRF-funded leukemia screening project lands NIH grant

Noah, leukemia survivor

Erin Marcotte, PhD, MPH, and Heather Nelson, PhD, MPH, of University of Minnesota are seizing the opportunity to turn small things into big hope for the future of childhood leukemia. In 2016, the pair received a grant from Children’s Cancer Research Fund (CCRF) to develop a new method to predict which children are at risk of developing acute lymphoblastic leukemia (ALL) — and perhaps one day prevent it.

Divide and conquer – a new way to study osteosarcoma

Using The Fight Osteosarcoma Together (FOT) Super Grant, funded in part by the Zach Sobiech Osteosarcoma Fund, Dr. Grohar will spend three years leading a research team to investigate a family of genes called MYC. His larger goal is to identify targeted treatments for osteosarcoma patients whose MYC genes have gone awry.

Six funding partners unite to defeat this formidable childhood cancer

If we want to defeat osteosarcoma, a formidable bone cancer, we must put a powerful force behind research. That’s why CCRF’s Zach Sobiech Osteosarcoma Fund is proud to unite with five funding partners to back The Fight Osteosarcoma Together (FOT) Super Grant, a new three-year, $1.5 million dollar grant to fight recurring osteosarcoma.

Developing a new way to stop the most aggressive leukemia

With support from an Accelerating Impact for Hard-to-Treat Cancer Award from Children’s Cancer Research Fund (CCRF), University of Virginia researcher John Bushweller is pursuing an innovative new way to treat this devastating disease. Bushweller has found that blocking the MLL protein from binding to DNA stops leukemia cell growth completely — like corking a bottle so that nothing can spill out. Now he and his team at UVA Cancer Center are developing drugs to disrupt the DNA binding process.

How one boy’s cells could power new treatments for ETMR

As young Jonah fought embryonal tumor with multilayered rosettes (ETMR), a very rare and aggressive pediatric brain tumor, he returned to the operating room at Weill Cornell Medicine Brain & Spine Center again and again. But the tenacious tumor kept coming back — and pediatric neurosurgeon Jeffrey Greenfield, MD, PhD, recognized the opportunity that presented on the laboratory bench.